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Technical University of Munich

Biomolecular Engineering & Design

Research on the physics of self-organization in biology. Image: Stefan Woidig / TUM

Based on a quantitative understanding of biomolecular interactions as well as modern AI tools, we use nucleic acid nanotechnology and protein design to create a new level of sophistication in biomolecular design. Our goals range from controlling molecular self-organization to recreating life from the bottom up, and programming cells for sensing, computation, actuation and therapeutics.

Subtopics

  • DNA Origami
  • Molecular Machines
  • Dynamic Molecular Structure

  • Protein Science, Evolution & Design
  • Functional Dynamics

  • Molecular Feedback Cycles
  • Cellular Model Systems
  • Multicellular Systems

News - Biomolecular Engineering & Design

Biomolecular Engineering & Design, CPA, Bioscience |

On December 5, 2025, new TUM Department of Bioscience professor gave an introductory lecture at the Center for Protein Assemblies (CPA).

Biomolecular Engineering & Design, CPA, Research, Bioscience |

Prof. Karen Alim and team have unraveled a new mechanism of signal transduction within large, multinucleated cells.

BioSysteM, Fundamental Science for Health, Fundamental Forces and Cosmic Evolution, Biomolecular Engineering & Design, ERC, ORIGINS, Research, Bioscience, Physics, Award |

EU funding for projects in biotechnology, medicine, and physics. Karoline Schäffner, Danny Nedialkova, Karen Alim and Roberto Rizzato from NAT are…

Biomolecular Engineering & Design, Research, Bioscience |

New “Dipid” structures combine lipid assembly principles with DNA programmability, enabling customizable containers for synthetic biology and…

BNMRZ, Biomolecular Engineering & Design, Accelerated Scientific Discovery, symposium, Research, Bioscience |

How do biomolecules breathe? This question guided the recent international symposium “Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms…

Fundamental Science for Health, Biomolecular Engineering & Design, ERC, CPA, Research, Bioscience, Award |

European funding for outstanding research into biotechnology at TUM

Biomolecular Engineering & Design, ORIGINS, Research, Bioscience |

Prof. Job Boekhoven and his team use simple molecules and chemical reactions in a bottom-up approach to replicate life in the lab.

BNMRZ, Fundamental Science for Health, Biomolecular Engineering & Design, Research, Bioscience |

Successful basic research at TUM for combating serious diseases

BioSysteM, Fundamental Science for Health, Biomolecular Engineering & Design, Accelerated Scientific Discovery, Bioscience |

Wübben Foundation interviewed new NAT School Prof. Thomas Schlichthärle for its “In Conversation with our Fellows” series

BioSysteM, Biomolecular Engineering & Design, Research, Bioscience |

BioSysteM EXplained with Friedrich Simmel

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