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  2. Research

Research

Accelerated Scientific Discovery
Image: LRZ SuperMUC. Bild: StMWK / Axel König

Biomolecular Engineering & Design
Image: Stefan Woidig / TUM

Clean Technology Solutions
Image: Astrid Eckert / TUM

Fundamental Forces & Cosmic Evolution
Image: Southern Ring Nebula by Webb Telescope / Public Domain

Fundamental Science for Health
Image: Nico Schramma / TUM

Quantum Science & Technologies
Image: Andreas Heddergott / TUM

Slide 1 of 6

At the TUM School of Natural Sciences, scientists from different disciplines work together on research topics in the fields of bioscience, chemistry, and physics. This fundamental research generates knowledge that facilitates a better understanding of our world and the development of new technologies.

To make research achievements efficiently accessible and visibly available to the outside world, TUM has established a Research Information System (FIS). It collects information on publication performance, awards, and research areas of individuals and organizational units at TUM.

Mission Statement

Discovery at all scales

Our School is committed to an integrative and dynamic learning environment engaged in pioneering research across the natural sciences. In three departments and in interdisciplinary integrative research centers, we explore, understand, and predict nature’s phenomena at all scales. Combining physical, chemical, and biological concepts bridged by engineering approaches, we create solutions for the fundamental societal challenges and educate the next generation.

Across three departments, nine integrative research institutes, five clusters of excellence, four collaborative research centers, contributions from the Max Planck Institutes, two venture labs, and numerous federally and EU-funded projects, the research focuses of the NAT School are concentrated on six main research areas.

Our research activities are bundled in three departments: Bioscience, Chemistry, and Physics. Each department is led by a Head of Department, and each professorship in our School belongs to one of these departments. 

The structure of the Professional Profiles, led by the respective Academic Program Directors (APDs), ensures the integration of research content with specific cross-disciplinary competencies into teaching. The aim is to develop these competency profiles further across universities by utilizing the full portfolio of TUM.

Clusters of Excellence are innovative, world-class research projects funded under the national Excellence Initiative, which connects universities with leading German research institutes and businesses. The School of Natural Sciences contributes to five of these clusters.

For key areas of interdisciplinary research, TUM has established its own central or integrative research centers, in which our School of Natural Sciences is strongly represented. The scientific opportunities resulting from the interdisciplinary diversity on the Garching campus attract scientists from all countries and fields.

The School of Natural Sciences participates in a number of interdisciplinary and inter-institutional research projects, which are funded by the German Research Foundation (DFG).

The high-tech campus Garching north of Munich is TUM's largest location and one of the most modern research and training facilities in Europe.

At the TUM School of Natural Sciences, cutting-edge research infrastructure enables pioneering discoveries in chemistry, physics, and the biosciences. From high-tech laboratories and core facilities to state-of-the-art research buildings and collaborative platforms – our scientists benefit from resources that drive innovation and scientific excellence

Latest News

FRM II, Clean Technology Solutions, Research, Physics | 08.06.2026

How battery electrolytes behave when you warm them up

Lea Westphal of the Technical University of Munich is the lead author of a new study that provides the most detailed, temperature-dependent picture of… [read more]

Quantum Science & Technologies, MCQST, Research, Chemistry | 02.06.2026

Proteins can be selectively controlled with radio waves

Biochemical Quantum Sensor Instead of Semiconductor [read more]

FRM II, Clean Technology Solutions, Research, Chemistry, Physics | 28.05.2026

Crystal defect with potential: positrons analyse battery materials

In "defect engineering", defects are purposely created in the atomic lattice to change material properties. An interdisciplinary research team has… [read more]

Public Outreach, Fundamental Forces and Cosmic Evolution, ORIGINS, Research, Physics | 26.05.2026

ZDF features research by TUM Prof. Karoline Schäffner

Zweites Deutsches Fernsehen explores the search for dark matter deep underground in the story “The Mystery of the Big Bang”. [read more]

Helmholtz, Fundamental Science for Health, Research, Physics | 13.05.2026

Giving X-ray Vision a Sense of Direction

A new method developed at Hereon reveals the orientation of the finest structures in materials. [read more]

Latest works

28788 Publications

Loading publications...

Article 2026
Search for the Higgs boson decay to a Z boson and a photon in pp collisions at s=13 TeV and 13.6 TeV with the ATLAS detector

Physics Letters B

Abstract: A search for the Higgs boson decay to a Z boson and a photon in the ℓℓ γ (ℓ=e,μ) final state is performed using pp collisions at s=13.6 TeV recorded with the ATLAS detector at the Large Hadron…

Aad, G.; Aakvaag, E.; Abbott, B. et al.

DOI
Article 2026
Photochemical Cyclization of Tertiary Buta-2,3-dienamides to β-Lactams Upon Triplet Energy Transfer

Angewandte Chemie - International Edition

Abstract: A series of N,N-disubstituted buta-2,3-dienamides was prepared from 3-butynoic acid and probed as substrates in a light-induced photocyclization. It was found that xanthen-9-one (10 mol%) promotes the…

Hofer, Johannes; Bertrams, Maria Sophie; Kerzig, Christoph; Bach, Thorsten

DOI
Article 2026
Microscopic mechanism of anyon superconductivity emerging from fractional Chern insulators

Newton

Abstract: Fractional quantum Hall (FQH) states and superconductors typically require contrasting conditions, yet recent experiments have observed them in the same device. A natural explanation is that mobile…

Pichler, Fabian; Kuhlenkamp, Clemens; Knap, Michael; Vishwanath, Ashvin

DOI
Article 2026
Primitive genotype-phenotype coupling in fuel-dependent synthetic cells with an autocatalyst

Chem

Abstract: The central dogma of molecular biology describes how genotype affects phenotype through the transfer of information from DNA to RNA to proteins and thus influences the cell’s traits. Reciprocally, the…

Soria-Carrera, Héctor; Kauling, Leonie; Boekhoven, Job

DOI
Article 2026
The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle

Molecular Cell

Abstract: The Hsp90 molecular chaperone system is regulated by numerous co-chaperones that modulate its function. In Saccharomyces cerevisiae , most of these cofactors can be deleted without affecting…

Engler, Sonja; Delhommel, Florent; Dodt, Christopher et al.

DOI
Article 2026
Switchable Reactivities of Metalated Phosphasilenes Regulated by Reversible 1,2-Metal Migration

Angewandte Chemie - International Edition

Abstract: Anionic reagents with silicon-containing double bonds, M(R)Si═ERn (E = main group elements), have garnered significant interest owing to their unique metal-mediated reactivity and their potential in…

Zhu, Huaiyuan; Dong, Shicheng; Liu, Xufang et al.

DOI
Article 2026
Evidence for a Spectral Break or Curvature in the Spectrum of Astrophysical Neutrinos from 5 TeV to 10 PeV

Physical Review Letters

Abstract: We report improved measurements of the all flavor astrophysical neutrino spectrum with IceCube by combining complementary neutrino samples in two independent analyses. Both analyses show evidence of a…

Abbasi, R.; Ackermann, M.; Adams, J. et al.

DOI
Article 2026
Distal peptide elongation by a protease-like ligase and two distinct carrier proteins

Chem

Abstract: Closthioamide (CTA) is a potent antibiotic with a unique polythioamide scaffold produced by Ruminiclostridium cellulolyticum . Unlike classical non-ribosomal peptide synthetases (NRPSs), which use…

Gude, Finn; Bohne, Annkathrin; Dell, Maria et al.

DOI
Article 2026
Influence of Methionine Oxidation on Protein Stability and Association Studied by Free Energy Simulations

Journal of Molecular Biology

Abstract: Cellular metabolic systems but also the extracellular environment can generate reactive oxygen species that lead to oxidation of methionine (MET) and interfere with protein folding and protein–protein…

Mauck, Tristan Alexander; Zacharias, Martin

DOI
Article 2026
Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering

Structure

Abstract: Incorporating metal cofactors into computationally designed protein scaffolds provides a versatile route to novel protein functions, including the potential for new-to-nature enzyme catalysis.…

Wagner Egea, Paula; Delhommel, Florent; Mustafa, Ghulam et al.

DOI
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TUM School of Natural Sciences

Technische Universität
München

Boltzmannstr. 10
85748 Garching

TUM ForTe

The Functional Unit 4 - TUM Office for Research and Innovation (TUM ForTe) provides scientists with professional and comprehensive advice on national and international research funding and technology transfer. TUM ForTe is also the first point of contact and central coordination office for all forms of research and business cooperation.

TUM ForTe Newsletter

The Newsletter on National and International Research Funding is published on a monthly basis and provides information on current calls for proposals and funding opportunities at TUM as well as information on national, European and international research programs.

Database for Funding Opportunities

The funding database ResearchConnect (formerly Open4Research) offers TUM researchers easy access to international funding programs for research, promotion of young researchers and technology transfer.

TUM Sustainable Futures Report

The Technical University of Munich is pursuing the goal of becoming holistically sustainable and climate-neutral through its TUM Sustainable Futures Strategy 2030 developed jointly with students and staff, the strategy defines key fields of action and measures.

Since 2024, the university has reported on progress toward these goals and the implementation of these measures in the TUM Sustainable Futures Report. This report ensures transparency and measurability by regularly presenting data-based updates on progress, actions, and developments.

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