Project of Prof. Nicole Strittmatter (Professor of Analytical Chemistry):
In some types of cancer, drugs gradually lose their effectiveness during treatment or fail to work from the start. This is especially common in pancreatic cancer. In her CITE project, Prof. Nicole Strittmatter aims to explore whether the cause lies in the tumor microenvironment, that is, whether cells and microbes within the tumor itself are inactivating the drugs. To study these interactions in isolation from drug metabolism by the rest of the body, Strittmatter is developing new analytical techniques. Using advanced imaging mass spectrometry methods, she plans to map the cells in the tumor microenvironment of pancreatic tumors and develop models to analyze how drugs are metabolized under realistic conditions.
Further information on the ERC Starting Grants can be found here.
Press contact